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Nuclear Receptor Signaling Atlas
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AES
Overview
Synonyms
AES ; AES-1 ; AES-2 ; AL024115 ; Aes ; ESP1 ; Esp1 ; GRG ; GRG5 ; Grg ; Grg-5 ; Grg5 ; LOC712353 ; R-esp1 ; TLE5 ; Tle5 ; aes ; amino enhancer of split ; gp130-associated protein GAM ; related to Drosophila groucho ; zgc:64216
NURSA Name
Amino terminal enhancer of split
Official Symbol
AES
No records found.
Description
AES is a member of the conserved Groucho/TLE family of transcriptional corepressors initially described as a nuclear receptor coregulator for the androgen receptor (AR).
Original References:
Yu X, Li P, Roeder RG and Wang Z (2001) Inhibition of androgen receptor-mediated transcription by amino-terminal enhancer of split. Mol. Cell. Biol. 21 4614-25 View Abstract | View PubMed
Miyasaka H, Choudhury BK, Hou EW and Li SS (1993) Molecular cloning and expression of mouse and human cDNA encoding AES and ESG proteins with strong similarity to Drosophila enhancer of split groucho protein. Eur. J. Biochem. 216 343-52 View Abstract | View PubMed
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