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Nuclear Receptor Signaling Atlas
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APPBP2
Overview
Synonyms
1300003O07Rik ; AI465480 ; APP-BP2 ; APPBP2 ; Appbp2 ; CG10695 ; CG10695-PA ; CG10695-PB ; CG10695-PC ; Dmel\CG10695 ; HS.84084 ; PAT1 ; Pat1 ; Pat1-PA ; Pat1-PB ; Pat1-PC ; amyloid beta precursor protein-binding protein 2 ; amyloid protein-binding protein 2 ; appbp2 ; protein interacting with APP tail 1 ; protein interacting with APP tail-1 ; wu:fb78e11 ; wu:fc25c09 ; zgc:76971
NURSA Name
Androgen receptor associated 67 kDa
Official Symbol
APPBP2
No records found.
Description
ARA67 is a microtubule-binding protein that has been shown to repress androgen receptor activity, possibly by influencing its subcellular localization.
Original References:
Zheng P, Eastman J, Vande Pol S and Pimplikar SW (1998) PAT1, a microtubule-interacting protein, recognizes the basolateral sorting signal of amyloid precursor protein. Proc. Natl. Acad. Sci. U.S.A. 95 14745-50 View Abstract | View PubMed
Zhang Y, Yang Y, Yeh S and Chang C (2004) ARA67/PAT1 functions as a repressor to suppress androgen receptor transactivation. Mol. Cell. Biol. 24 1044-57 View Abstract | View PubMed
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