Error
Your session has expired. Please click "Refresh" to refresh the page.
Nuclear Receptor Signaling Atlas
A research resource for the nuclear receptor signaling community
Newsletter Sign Up
RBM14
Overview
Synonyms
1300007E16Rik ; COAA ; CoAA ; PSP2 ; RBM14 ; RNA binding motif protein 14 ; RNA-binding motif protein 14 ; RNA-binding protein 14 ; RRM-containing coactivator activator/modulator ; Rbm14 ; SIP ; SYT-interacting protein ; SYTIP1 ; Sytip ; TMEM137 ; coactivator activator ; im:7053198 ; p16 ; p16K ; paraspeckle protein 2 ; rbm14a ; synaptotagmin interacting protein ; synaptotagmin-interacting protein ; transmembrane protein 137 ; wu:fc08a04 more...
Synonyms
1300007E16Rik; COAA; CoAA; PSP2; RBM14; RNA binding motif protein 14; RNA-binding motif protein 14; RNA-binding protein 14; RRM-containing coactivator activator/modulator; Rbm14; SIP; SYT-interacting protein; SYTIP1; Sytip; TMEM137; coactivator activator; im:7053198; p16; p16K; paraspeckle protein 2; rbm14a; synaptotagmin interacting protein; synaptotagmin-interacting protein; transmembrane protein 137; wu:fc08a04; zgc:110682
NURSA Name
Coactivator activator
Official Symbol
RBM14
No records found.
Description
CoAA is an RNA-recognition motif-containing protein which coactivates nuclear receptor-mediated transcription through synergistic interactions with other coregulators such as TRBP and CBP. An alternative splice form of CoAA that functions as transcriptional repressor was termed coactivator modulator CoAM. CoAA/CoAM modulate mRNA splicing and affect both transcription and splicing in a promoter-preferential manner.
Original References:
Iwasaki T, Chin WW and Ko L (2001) Identification and characterization of RRM-containing coactivator activator (CoAA) as TRBP-interacting protein, and its splice variant as a coactivator modulator (CoAM). J. Biol. Chem. 20 33375-83 View Abstract | View PubMed
Brett D, Whitehouse S, Antonson P, Shipley J, Cooper C and Goodwin G (1997) The SYT protein involved in the t(X;18) synovial sarcoma translocation is a transcriptional activator localised in nuclear bodies. Hum. Mol. Genet. 6 1559-64 View Abstract | View PubMed
Ortholog
Gene
RNA
Protein
GO Terms
Crystal Structures
Post-Translational Modifications
Protein-Protein Interactions
Targeting miRNAs
Pathways
Pharmacogenomics
Datasets
Reagents
Diseases
Clinical Trials
Animal Models
Drugs
Literature