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Nuclear Receptor Signaling Atlas
A research resource for the nuclear receptor signaling community
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Molecules Found. Use the Filter to narrow the listing.
Molecule Type
GO Terms
Disease
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TypeSymbolNameDescription
Ligand11Dcort11-deoxycortisol The 17-hydroxycorticosteroid 11-deoxycortisol is a precursor of cortisol, the main glucocorticoid secreted by the adrendal cortex. 11-deoxycortisol is an agonist of the glucocorticoid receptor (GR...
Ligand125DVD31,25-dihydroxyvitamin D3 1,25-dihydroxyvitamin D3 is the active hormonal form of vitamin D and the primary natural ligand of the vitamin D receptor (VDR), a member of the nuclear receptor superfamily of transcription...
Ligand13cRA13-cis RA Retinoids are a group of vitamin A analogues that have shown promise as therapeutic agents. 13-cis retinoic acid is a stereoisomer of all-trans retinoic acid, and is a selective agonist for...
Ligand15-deoxy-Δ-12,14-PGJ215-deoxy-Δ-12,14-PGJ2 The cyclopentenone prostaglandin 15-deoxy-δ-12,14-PGJ2 is a potent natural agonist of peroxisome proliferator-activated receptor-γ (PPARγ), a member of the nuclear receptor superfamily...
Ligand15DPGJ215-Deoxy-Δ-12,14-prostaglandin The cyclopentenone prostaglandin 15-deoxy-δ-12,14-PGJ2 is a potent natural agonist of peroxisome proliferator-activated receptor-γ (PPARγ), a member of the nuclear receptor superfamily...
Ligand16KE216-Ketoestradiol 16-Ketoestradiol is found in the estrogen patch. The estrogen patch is a delivery system for estradiol used as hormone replacement therapy to treat the symptoms of menopause, such as hot...
Ligand17αE217α-estradiol 17α-estradiol has historically been considered a hormonally inactive isomer of 17β-estradiol, the natural ligand for the estrogen receptor (ER) subfamily of the nuclear receptor superfamily...
Ligand17αEE217α-ethinylestradiol EE2 is a semisynthetic alkylated agonist of the estrogen receptor (ER) subfamily of the nuclear receptor superfamily of transcription factors. It has high estrogenic potency when administered...
Ligand17βE217β-estradiol 17β-estradiol is the most potent of the mammalian estrogenic steroids, and is a natural agonist for ERα and ERβ. In humans, it is produced primarily by the cyclic ovary and the placenta, but is...
Ligand18OHRA18-OH-retinoic acid 18-hydroxy retinoic acid is metabolite of all-trans retinoic acid that is a panagonist for members of the retinoic acid receptor (RAR) subfamily of the nuclear receptor superfamily of...
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