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Nuclear Receptor Signaling Atlas
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16KE2
Overview
Name
16-Ketoestradiol
Synonyms
16-Ketoestradiol; 16-Oxoestradiol; 566-75-6; NSC 51169; CHEBI:34165; (17beta)-3,17-dihydroxyestra-1(10),2,4-trien-16-one; Keto; UNII-6CE096RR70; 16-Keto-estradiol; 16-Oxoestradiol-17b; 16-Oxo-17b-estradiol; 16-keto-17b-Estradiol; 16-Oxoestradiol-17|A; 16-Oxo-17beta-estradiol; 16-Oxo-17|A-estradiol; 16-Keto-17beta-estradiol; AC1L25BR; 16-Keto 17|A-Estradiol; SCHEMBL928512; CHEMBL1627347; DTXSID5040386; HMDB00406; KJDGFQJCHFJTRH-YONAWACDSA-N; 6CE096RR70; NSC51169 more...
Synonyms
16-Ketoestradiol; 16-Oxoestradiol; 566-75-6; NSC 51169; CHEBI:34165; (17beta)-3,17-dihydroxyestra-1(10),2,4-trien-16-one; Keto; UNII-6CE096RR70; 16-Keto-estradiol; 16-Oxoestradiol-17b; 16-Oxo-17b-estradiol; 16-keto-17b-Estradiol; 16-Oxoestradiol-17|A; 16-Oxo-17beta-estradiol; 16-Oxo-17|A-estradiol; 16-Keto-17beta-estradiol; AC1L25BR; 16-Keto 17|A-Estradiol; SCHEMBL928512; CHEMBL1627347; DTXSID5040386; HMDB00406; KJDGFQJCHFJTRH-YONAWACDSA-N; 6CE096RR70; NSC51169; ZINC4721188; LMST02010047; NSC-51169; ZINC04721188; AKOS027378612; API0000143; AK386112; PL000999; C14383; 1,3,5(10)-Estratriene-3,17b-diol-16-one; 1,3,5(10)-Estratrien-3,17-beta-diol-16-one; 1,3,5(10)-Estratriene-3,17|A-diol-16-one; 3,17b-Dihydroxyestra-1,3,5(10)-trien-16-one; C-44099; 3,17-Dihydroxyestra-1,3,5(10)-trien-16-one #; Estra-1,3,5(10)-triene-3beta,17beta-diol-16-one; (17|A)-3,17-Dihydroxyestra-1,3,5(10)-trien-16-one; Estra-1,3,5(10)-trien-16-one, 3,17-dihydroxy-, (17.beta.)-; Estra-1,5(10)-trien-16-one, 3,17-dihydroxy-, (17.beta.)-; Estra-1,3,5(10)-trien-16-one, 3,17-dihydroxy-, (17beta)- (9CI); (1S,10R,11S,14R,15S)-5,14-DIHYDROXY-15-METHYLTETRACYCLO[8.7.0.0(2),?.0(1)(1),(1)?]HEPTADECA-2,4,6-TRIEN-13-ONE; (8R,9S,13S,14S,17R)-3,17-Dihydroxy-13-methyl-7,8,11,12,13,14,15,17-octahydro-6H-cyclopenta[a]phenanthren-16(9H)-one; (8R,9S,13S,14S,17R)-3,17-dihydroxy-13-methyl-7,8,9,11,12,14,15,17-octahydro-6H-cyclopenta[a]phenanthren-16-one
PubChem ID
ChEBI ID
IUPHAR ID
Not available
CAS Registry ID
566-75-6
Jmol
Not available
Description
16-Ketoestradiol is found in the estrogen patch. The estrogen patch is a delivery system for estradiol used as hormone replacement therapy to treat the symptoms of menopause, such as hot flashes and vaginal dryness, and to prevent osteoporosis. Originally marketed as Vivelle (Novartis), it was discontinued in 2003 and reintroduced in a smaller form as Vivelle-Dot . Although the estrogen is given transdermally rather than in the standard oral tablets, the estrogen patch carries similar risks and benefits as more conventional forms of estrogen-only hormone replacement therapy.
Pathways
Pharmacogenomics
Nuclear Receptors
Datasets
Literature