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Nuclear Receptor Signaling Atlas
A research resource for the nuclear receptor signaling community
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11Dcort
Overview
Name
11-deoxycortisol
Synonyms
11-deoxycortisol ; 11Dcort ;
ChEBI ID
PubChem ID
CAS Registry ID
152-58-9
Jmol
Not available
Description
The 17-hydroxycorticosteroid 11-deoxycortisol is a precursor of cortisol, the main glucocorticoid secreted by the adrendal cortex. 11-deoxycortisol is an agonist of the glucocorticoid receptor (GR) and mineralocorticoid receptor (MR), steroid receptor members of the nuclear receptor superfamily of transcription factors. The synthetic formulation, cortodoxone, has anti-inflammatory activity.
Pathways
Pharmacogenomics
Nuclear Receptors
Datasets
Literature