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Nuclear Receptor Signaling Atlas
A research resource for the nuclear receptor signaling community
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13cRA
Overview
Name
13-cis RA
Synonyms
13-cis RA ; 13cRA ;
ChEBI ID
PubChem ID
CAS Registry ID
4759-48-2
Jmol
Not available
Description
Retinoids are a group of vitamin A analogues that have shown promise as therapeutic agents. 13-cis retinoic acid is a stereoisomer of all-trans retinoic acid, and is a selective agonist for the retinoid acid receptor (RAR) subfamily of the nuclear receptor superfamily of transcription factors. At high concentrations it inhibits sebaceous gland function and keratinization and has been used in the treatment of dermatological conditions including nodular acne and rosacea, as well as in inflammatory joint conditions such as sacroiliitis. It is teratogenic in human and animals.
Pathways
Pharmacogenomics
Nuclear Receptors
Datasets
Pharmacology
Carriers
Enzymes
Targets
Transporters
Literature