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Nuclear Receptor Signaling Atlas
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15-deoxy-Δ-12,14-PGJ2
Overview
Name
15-deoxy-Δ-12,14-PGJ2
Synonyms
; 15-deoxy-Δ-12,14-PGJ2
PubChem ID
CAS Registry ID
89886-60-2
Jmol
Not available
Description
The cyclopentenone prostaglandin 15-deoxy-δ-12,14-PGJ2 is a potent natural agonist of peroxisome proliferator-activated receptor-γ (PPARγ), a member of the nuclear receptor superfamily of transcription factors. It influences a variety of cellular processes, including adipocyte differentiation and modulation of the immune response by mediating lymphocyte apoptosis.
Pathways
Pharmacogenomics
Nuclear Receptors
Datasets
Literature