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Nuclear Receptor Signaling Atlas
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NR2F2
Overview
Synonyms
0005/12 ; 0042/01 ; 0106/18 ; 0114/20 ; 0351/01 ; 0598/01 ; 0861/07 ; 2700033K02Rik ; 9430015G03Rik ; ADP-ribosylation factor related protein 1 ; ARP-1 ; ARP1 ; Aporp1 ; BcDNA:GH08189 ; CG11502 ; CG11502-PA ; CG11502-PB ; CG11502-PC ; CG11502-PE ; CG18158 ; COUP transcription factor 2 ; COUP transcription factor II ; COUP-TF II ; COUP-TF2 ; COUP-TFII more...
Synonyms
0005/12; 0042/01; 0106/18; 0114/20; 0351/01; 0598/01; 0861/07; 2700033K02Rik; 9430015G03Rik; ADP-ribosylation factor related protein 1; ARP-1; ARP1; Aporp1; BcDNA:GH08189; CG11502; CG11502-PA; CG11502-PB; CG11502-PC; CG11502-PE; CG18158; COUP transcription factor 2; COUP transcription factor II; COUP-TF II; COUP-TF2; COUP-TFII; COUPTFB; COUPTFII; COUPTFbeta; COUPb; Dmel\CG11502; EAR3; NF-E3; NR2F1; NR2F2; NR2F3; Nr2f2; SEVEN-UP; SVP; SVP-1; SVP1; SVP40; Svp; TFCOUP2; Tcfcoup2; Tfcoup2; apolipoprotein A-I regulatory protein 1; apolipoprotein A1 regulatory protein 1; apolipoprotein AI regulatory protein 1; apolipoprotein regulatory protein 1; chicken ovalbumin upstream promoter transcription factor 2; chicken ovalbumin upstream promoter-transcription factor I; ck16; complementation group 7; don; down-and-out; fc94g08; l(3)07842; l(3)87Bd; l(3)ck16; l(3)j2E2; l(3)rA028; l(3)rL069; nr2f2; nuclear receptor subfamily 2 group F member 2; nuclear receptor subfamily 2, group F, member 1; ovalbumin upstream promoter beta nuclear receptor; seven Up; seven-up related 40; sevenup; svp; svp-PA; svp-PB; svp-PC; svp-PE; svp40; svp[40]; transcription factor COUP 2; wu:fc94g08
NURSA Name
Chicken ovalbumin upstream promoter transcription factor II
Official Symbol
NR2F2
No records found.
Description
COUP-TFII is a member of the COUP-TF orphan subfamily of the nuclear receptor superfamily of transcription factors. It has roles in angiogenesis, vascular remodeling and heart development. COUP-TFII is expressed in tissues in all major physiological systems (central nervous system (CNS), endocrine, metabolic, gastrointestinal, immune, reproductive, cardiovascular, respiratory and structural) with particularly high levels in the adrenal gland, kidney, ovary, uterus and vas deferens. Targeted deletion (knockout) of COUP-TFII results in insulin secretion and sensitivity defects, defects in the radial and anterior patterning of the stomach, and angiogenesis and heart development defects.
Original References:
Wang LH, Ing NH, Tsai SY, O'Malley BW and Tsai MJ (1991) The COUP-TFs compose a family of functionally related transcription factors. Gene Expr. 1 207-16 View Abstract | View PubMed
Ladias JA and Karathanasis SK (1991) Regulation of the apolipoprotein AI gene by ARP-1, a novel member of the steroid receptor superfamily. Science 251 561-5 View Abstract | View PubMed
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